Birth Control

Progesterone Cream

Met & Pregnancy

Ob/Gyn News

Doc Lists


Abnormal Bleeding

About me





Dr. Speroff



Updated May/June 2003:

Differential Effects of Raloxifene and Estrogen on Insulin Sensitivity in Postmenopausal Women

Updated April 2003:

HRT and Incidence of Alzheimer Disease in Older Women

Hair loss (see last 2 paragraphs)

FDA asks HHS Inspector General to investigate FDA-sponsored clinical trial

Effects of Internet Behavioral Counseling on Weight Loss in Adults at Risk for Type 2 Diabetes

TV Watching and Other Sedentary Behaviors in Relation to Risk of Obesity and Type 2 Diabetes Mellitus in Women

Medical myth: Bimanual pelvic examination is a reliable decision aid in the investigation of acute abdominal pain or vaginal bleeding

Cervical cancer and use of hormonal contraceptives

Six-month efficacy of benfluorex vs. placebo or metformin in diet-failed type 2 diabetic patients

Insulin resistance in PCOS patients is associated with elevated plasma homocysteine

Association of Endogenous Sex Hormones and Insulin Resistance among Postmenopausal Women

Evidence for Abnormal Granulosa Cell Responsiveness to Follicle-Stimulating Hormone in PCOS Women

Central fat predicts deterioration of insulin secretion index and fasting glycaemia

Metabolic and cardiovascular effects of very-low-calorie diet therapy in obese patients with Type 2 diabetes

Effect of Pioglitazone Compared with Metformin on Glycemic Control and Indicators of Insulin Sensitivity in Recently Diagnosed Patients with Type 2 Diabetes

Addition of rosiglitazone to metformin is most effective in obese, insulin-resistant patients with type 2 diabetes

Updated March 2003:

A Cohort Study of the Incidence of Serious Acute Liver Injury in Diabetic Patients Treated With Hypoglycemic Agents

Metformin Blunts Stress-Induced Hyperglycemia after Thermal Injury

Clinical and personal relationships between BCP and HRT use among US women physicians

Soy protein and isoflavone effects on vasomotor symptoms in peri- and postmenopausal women

Menopausal transition and psychological development

Creatine supplementation has no effect on human muscle protein turnover at rest in the post absorptive or fed states

VLDL-triglyceride kinetics during hyperglycemia-hyperinsulinemia: effects of sex and obesity

Differences in the use of combined oral contraceptives amongst women with and without acne

The risk of venous thromboembolism in women prescribed cyproterone acetate in combination with ethinyl estradiol

Polymorphism in the peroxisome proliferator-activated receptor-gene in PCOS women

Exercise and Diet in Obesity Treatment

Insulin resistance is a poor predictor of type 2 diabetes in individuals with no family history of disease

Cardiac Transcriptome Analysis in Obesity-Related Hypertension

DASH Diet Lowers Blood Pressure and Lipid-Induced Oxidative Stress in Obesity

The Kidney, Hypertension, and Obesity

An increase in lipoprotein oxidation and endogenous lipid peroxides in serum of obese women

Family History of Hypertension and Type 2 Diabetes in Relation to Preeclampsia Risk

Fat distribution in non-obese girls with and without precocious pubarche

Ultrasound examination of polycystic ovaries: is it worth counting the follicles?

Help your patients control their weight

A relationship between serum ferritin and insulin resistance

HRT containing progestins and given continuously increases breast carcinoma risk in Sweden

Soluble Tumor Necrosis Factor- Receptors in Young Obese Subjects With Normal and Impaired Glucose Tolerance

A Comparison of the Prevalence of the Metabolic Syndrome Using Two Proposed Definitions

Changes in Diabetes Self-Care Behaviors Make a Difference in Glycemic Control

Lifestyle Modification to Improve Blood Pressure Control in Individuals With Diabetes

The Hormone Therapy Dilemma: Women Respond

Added Feb. 2003:

Effect of long-term treatment with low-dose mifepristone on the endometrium

Progesterone hastens diabetes progression in murine model

Who needs more doctors

Spanish Patient Education Materials

Reading Room several books on medicine

Beth Israel Deaconess Medical Center

Informacion en Espanol

Carb metabolism in women who used OCs

Greens to Launch New Scare Campaign

Tera's PCOS Article

The management of obesity

Vitamin A Supplements May Hurt Bones

Type 2 Diabetes Risk Factor Eating nuts and peanut butter prevents type 2 diabetes

Reproductive Medicine FDA approves Bravelle for in vitro fertilization

Nutrition How low does your folate go Frequently Answered Questions

Proof Dr Lee gets money from cream sales to his PRI

Ortho TriCyclen Lo

IMPAC Managing Complications in Pregnancy and Childbirth

Visceral fat is more important than peripheral fat for endometrial thickness and bone mass in healthy postmenopausal women

The relationship of race to women's use of health information resources

Relationship between polycystic ovaries, body mass index and IR

Valproate, bipolar disorder and PCOS

Improvements in insulin sensitivity and -cell function (HOMA) with weight loss in the severely obese

Proinsulin and acute insulin response independently predict NIDDM in menreport from 27 years of follow-upstudy

The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes

Multiple Indexes of Lipid Availability Are Independently Related to Whole Body Insulin Action in Healthy Humans

Gender differences in the prevalence, clinical features and response to cabergoline in hyperprolactinemia

Dietary Composition in Restoring Reproductive and Metabolic Physiology in Overweight Women with PCOS

Troglitazone Therapy Improves Endothelial Function to Near Normal Levels in Women with PCOS

Circulating Ghrelin Concentrations in PCOS

Risk factors associated with peri- and postmenopausal bone loss: does HRT prevent weight loss-related bone loss?

Childhood obesity: a societal problem to solve

Treatment of obesity: an update on anti-obesity medications

Weight loss causes increased mortality

Editorial: Your message to patients: Supersize, shorter life

Commentary: A Clinical View of the Obesity Problem -- Science

Commentary: A War on Obesity, Not the Obese

Commentary: Obesity and the Environment - Where Do We Go from Here?

Reduced exercise arteriovenous O2 difference in Type 2 diabetes

Sequential treatment of metformin and Clomid in Clomid-resistant PCOS women

Making decisions about HRT

Reduction of risk factors following lifestyle modification programme in subjects with NIDDM

Insulin and the "Thrifty" Woman: The Influence of Insulin During Pregnancy on Gestational Weight Gain and Postpartum Weight Retention

Clinical evaluation of pioglitazone in patients with type 2 diabetes using alpha-glucosidase inhibitor and examination of its efficacy profile

Dietary glycemic index, glycemic load and ovarian cancer risk

Hepatocellular adenoma and PCOS

Reduced vaginal bleeding in postmenopausal women who receive Activella versus Premarin/Provera

Improved beta-cell function after standardized weight reduction in severely obese subjects

Validation of a Counseling Strategy to Promote the Adoption and the Maintenance of Physical Activity by Type 2 Diabetic Subjects

Dietary Fat Intake as Risk Factor for the Development of Diabetes

Association Between Regional Adipose Tissue Distribution and Both Type 2 Diabetes and Impaired Glucose Tolerance in Elderly Men and Women

Aging Per Se Does Not Influence Glucose Homeostasis

Acarbose Improves Glycemic Control in Overweight Type 2 Diabetic Patients Insufficiently Treated With Metformin

Calcium, vitamin D, milk consumption, and hip fractures: a prospective study among postmenopausal women

Current issues in hormonal contraception

Direct Measure of Insulin Sensitivity with the Hyperinsulinemic-Euglycemic Clamp and Surrogate Measures of Insulin Sensitivity with the OGTT

Differential Effects of Rosiglitazone and Metformin on Adipose Tissue Distribution and Glucose Uptake in Type 2 Diabetic Subjects

Prediction of Type 2 Diabetes Using Simple Measures of Insulin Resistance

High-fiber rye bread and insulin secretion and sensitivity in healthy postmenopausal women

Comparison of the Clinical Efficacy and Safety of Flutamide versus Flutamide plus an Oral Contraceptive in the Treatment of Hirsutism

Risk Factors and Secondary Prevention in Women with Heart Disease: The Heart and Estrogen/progestin Replacement Study

Abortion, legal since 1973, still shapes, divides doctors

Providing women with information on treatment options does not affect choices

Study offers further evidence that HRT does not protect against cardiovascular disease

Big story of 2002 was that something failed to work

Less invasive procedure could treat some infertile women

MedPanel releases HRT study results

Diet and Sex Hormones in Girls

Effect of Exercise on Total and Intra-abdominal Body Fat in Postmenopausal Women

Hormonal Factors in Migraine

Hormonal Therapy: Current and New Directions

Effect of long-term treatment with low-dose mifepristone on the endometrium

Low-dose combination of flutamide, metformin and an oral contraceptive for non-obese, young women with PCOS

Hormonal Profile of Women with Self-Reported Symptoms of Oligomenorrhea and/or Hirsutism

Regulation of HOXA-10 Expression by Testosterone in Vitro and in the Endometrium of PCOS Patients

Insulin Resistance in Type 2 Diabetes: Association with Truncal Obesity, Impaired Fitness, and Atypical Malonyl Coenzyme A Regulation

Years of Life Lost Due to Obesity

Oral Treatments for Type II Diabetes in Patients with Cardiovascular Disease

Gender differences in factors influencing insulin resistance in elderly hyperlipemic non-diabetic subjects

How hyperglycemia promotes atherosclerosis: molecular mechanisms

Dietary Patterns and Risk of Hypertension, Type 2 Diabetes Mellitus, and Coronary Heart Disease

Obesity in Adulthood and Its Consequences for Life Expectancy: A Life-Table Analysis

Glycemic Effects of Postmenopausal Hormone Therapy: The Heart and Estrogen/progestin Replacement Study

Prescribing Oral Contraceptives for Women Older Than 35 Years of Age

Uterine Fibroids Study Uterine artery embolization effective treatment for fibroids

Uterine Fibroids Study Uterine artery embolization effective treatment for fibroids

The making of a disease: female sexual dysfunction

Overeating Among Adolescents: Prevalence and Associations With Weight-Related Characteristics and Psychological Health

Prevalence of Obesity, Diabetes, and Obesity-Related Health Risk Factors

Efficacy of static magnetic field therapy in chronic pelvic pain

Added Dec. 2002:

The Atherogenic Lipoprotein Profile Associated With Obesity and IRe Is Largely Attributable to Intra-Abdominal Fat

A Randomized Trial of Sibutramine in the Management of Obese Type 2 Diabetic Patients Treated With Metformin

Abdominal Obesity and Ethnic Differences in Diabetes Awareness, Treatment, and Glycemic Control

Association of Self-perceived Body Weight Status with Dietary Reporting by U.S. Teens

Cost of In-Patient Care over 7 Years among Surgically and Conventionally Treated Obese Patients

Impact of Dieting Status and Dietary Restraint on Postexercise Energy Intake in Overweight Women

Impact of Visceral Fat on Blood Pressure and Insulin Sensitivity in Hypertensive Obese Women"

Metabolic Response to a Mixed Meal in Obese and Lean Women from Two South African Populations

Costs Associated With the Primary Prevention of Type 2 Diabetes Mellitus in the Diabetes Prevention Program

Effects of Injectable or Implantable Progestin-Only Contraceptives on Insulin-Glucose Metabolism and Diabetes Risk

Race, Menopause, Health-Related Quality of Life, and Psychological Well-Being in Obese Women

HRT and cancer: quantifying the risk

Life Course Influences on Insulin Resistance

Randomized Controlled Community-Based Nutrition and Exercise Intervention Improves Glycemia and Cardiovascular Risk Factors in Type 2 Diabetic Patients in Rural Costa Rica

Rosiglitazone Improves Insulin Sensitivity and Lowers Blood Pressure in Hypertensive Patients

OB-GYN-L Re ny times article

Effects of Diets Enriched in Saturated (Palmitic), Monounsaturated (Oleic), or trans (Elaidic) Fatty Acids on Insulin Sensitivity and Substrate Oxidation in Healthy Adults

Doctor accused of giving false information to drug trial

Physical Activity and the Metabolic Syndrome in a Tri-ethnic Sample of Women

Diabetic ketoacidosis associated with Metabolife

Should patients with PCOS be treated with Metformin

Six weeks of ginkgo supplement does not improve memory, learning, concentration

Low adiponectin levels related to development of type 2 diabetes

Low GH, high ATCH responses to glucagon found in obese patients

Six weeks of ginkgo supplement does not improve memory, learning, concentration

Breast Cancer Study finds young women's knowledge, health practices lacking

75% of women don't make healthful lifestyle choices Cardiovascular Disease

NDA accepted for filing by FDA for extended-regimen oral contraceptive

Contraception Bone loss in Depo-Provera users largely reversible

Morbidly obese women exhibit impaired triglyceride metabolism

Women prone to repeat miscarriage show increased prevalence of insulin resistance

U.K. women are ignoring health advice, lack understanding

Women's Health Nurse's Health Study shows being overweight increases ovarian cancer risk

Preconception Health Care

How to Prepare for Pregnancy

Childbirth and incontinence: a prospective study on anal sphincter morphology and function before and early after vaginal delivery

Herbal medicine in pregnancy

A Specific Elevation in Tissue Plasminogen Activator Antigen in Women with PCOS

Letter: Has medicalisation of childbirth gone too far?

Premature pubarche in girls is associated with functional adrenal but not ovarian hyperandrogenism

Prevalence of Type II diabetes mellitus and insulin resistance in parents of women with PCOS

Increased TSA levels are associated with previous GDM, suggesting a chronic mild systemic inflammatory response is an early feature of the metabolic syndrome and that GDM may be a window for its investigation

Chronic pelvic pain: the gynaecological enigma

The Methionine 196 Arginine Polymorphism in Exon 6 of the TNF Receptor 2 Gene (TNFRSF1B) Is Associated with PCOS and Hyperandrogenism

Pearls: physician-patient relationships

Benefits and Risks of Psychiatric Medications During Pregnancy

The Cardiovascular Risk Factor Homocysteine Is Not Elevated in Young Women with Hyperandrogenism or Hypoestrogenism

Infertility websites fail to meet quality standards

Review of pregnancy labeling of prescription drugs: Is the current system adequate to inform of risks?

Luteal phase support in infertility treatment: a meta-analysis of the randomized trials

Myocardial infarction and third generation oral contraceptives: aggregation of recent studies

Depo-Provera contraceptive may increase risk of cardiovascular disease

Insulin, insulin-like growth factor-1, and insulin resistance in women with pregnancy-induced hypertension

Impaired tolerance for glucose in women with recurrent vaginal candidiasis

Laparoscopic excision of large ovarian cysts

Special focus:

Reference 1

Top surgeon acknowledges phony data, is suspended.

Rising Health Premiums Fail to Stir Consumers -- Yet

Biological Journals and Abbreviations

Association of Health Literacy With Diabetes Outcomes

Medicine men at NIH

Doctor believed that patients should be told what was best for them

Last Update:

May 27, 2003